Prelims (PDF 37 KB)
Contents (PDF 25 KB)
pp. v-vi.
Foreword (PDF 25 KB)
pp. vii-viii.
Introduction (PDF 33 KB)
pp. ix-xi.
Co-workers and Associates (PDF 25 KB)
pp. xiii-xv.
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Chapter 1
Measurements on Microscopic Images
Pathology of Organ Structure by Analysis and Interpretation of Images, Tohru Takahashi, pp. 1-23.
© 2005 (First Edition), 2011 (Second Edition) by SciPress, Tokyo.
[Full text] (PDF 2 MB)
a) Morphometry of arteries on microscopic images, pp. 1-12
b) Morphometry of airways—what part of bronchial tree constricts in
asthmatic attack?, pp. 12-18
c) Standardized morphometry of airways in normal and diseased lungs, pp. 18-23
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Chapter 2
Stereology and Its Application to Pathology
Pathology of Organ Structure by Analysis and Interpretation of Images, Tohru Takahashi, pp. 25-67.
© 2005 (First Edition), 2011 (Second Edition) by SciPress, Tokyo.
[Full text] (PDF 4.3 MB)
a) Evaluation of paraquat-induced atelectasis, pp. 26-29
b) Langerhans islets of the pancreas in diabetics, pp. 30-37
c) Morphometry of metastatic tumor nodules in the liver, pp. 37-42
d) Alveolar surface area of normal and emphysematous lungs, pp. 42-47
e) Remodeling of alveolar structure in paraquat lung, pp. 47-54
f) Changes of bone trabeculae in osteoporosis—a cylindrical model, pp. 54-60
g) The mean radius of hepatic lobules—another cylindrical model, pp. 60-66
h) Problems that cannot be solved by stereology, pp. 66-67
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Chapter 3
The Basic Structure of Human Liver from the Viewpoint of Vascular Architecture
Pathology of Organ Structure by Analysis and Interpretation of Images, Tohru Takahashi, pp. 69-95.
© 2005 (First Edition), 2011 (Second Edition) by SciPress, Tokyo.
[Full text] (PDF 3.4 MB)
a) The unitary structure—different concepts, pp. 69-74
b) The microvasculature of human liver and its functional significance, pp. 74-81
c) Quantitative expression of vasculature pattern, pp. 82-87
d) Why does the vascular pattern differ among the organs ?, pp. 87-92
e) Pathogenesis of hepatic failure in cirrhosis, pp. 93-95
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Chapter 4
Three-D Structural Analysis: Method and Examples of Application
Pathology of Organ Structure by Analysis and Interpretation of Images, Tohru Takahashi, pp. 97-151.
© 2005 (First Edition), 2011 (Second Edition) by SciPress, Tokyo.
[Full text] (PDF 10.4 MB)
1) Preparation of serial sections, pp. 97-98
2) Abstraction of 2-D images from serial sections, pp. 98-100
3) Manual reconstruction, pp. 101-103
4) Computer-assisted reconstruction, pp. 103-105
5) Examples of 3-D reconstruction, pp. 105-151
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a) The vasa vasorum of aortic wall, pp. 105-108
b) Three-D mapping of vascular lesions of lungs in pulmonary hypertension, pp. 108-118
c) Hypoplastic zone of myenteric plexus in Hirschsprung's disease, pp. 119-124
d) Three-D mapping of airway obstruction in bronchiolitis obliterans, pp. 125-126
e) Multistep carcinogenesis of the large intestine, pp. 126-130
f) The development and extension of hepatohilar bile duct carcinoma, pp. 131-135
g) Intraductal papilloma of breast: extension and cancer development, pp. 136-140
h) Three-D microanatomy and pathology of human pancreas, pp. 140-149
i) The microanatomy of terminal liver vessels and bile ducts, pp. 149-151
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Chapter 5
The Structure of Adenocarcinoma and the Structural Differentiation
Pathology of Organ Structure by Analysis and Interpretation of Images, Tohru Takahashi, pp. 153-169.
© 2005 (First Edition), 2011 (Second Edition) by SciPress, Tokyo.
[Full text] (PDF 3.6 MB)
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Chapter 6
Morphogenesis of Cirrhosis from Chronic Hepatitis
Pathology of Organ Structure by Analysis and Interpretation of Images, Tohru Takahashi, pp. 171-194.
© 2005 (First Edition), 2011 (Second Edition) by SciPress, Tokyo.
[Full text] (PDF 5.6 MB)
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Chapter 7
Some Other Topological Problems in Microscopic Pathology
Pathology of Organ Structure by Analysis and Interpretation of Images, Tohru Takahashi, pp. 195-223.
© 2005 (First Edition), 2011 (Second Edition) by SciPress, Tokyo.
[Full text] (PDF 3.2 MB)
a) Changes of pattern from chronic hepatitis to cirrhosis, pp. 195-202
b) Two types of glandular tumors: papillary and tubular, pp. 202-208
c) Hepatocellular carcinoma: two different types, pp. 208-210
d) The pattern of zonal hepatocellular necrosis: Is the acinar theory tenable?, pp. 210-223
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Chapter 8
The Adequate Classification of Form in Pathology
Pathology of Organ Structure by Analysis and Interpretation of Images, Tohru Takahashi, pp. 225-248.
© 2005 (First Edition), 2011 (Second Edition) by SciPress, Tokyo.
[Full text] (PDF 2.9 MB)
a) Adequate classification of liver cirrhosis, pp. 227-234
b) Adequate classification of carcinomatous and precarcinomatous cells, pp. 235-248
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i) Adenocarcinoma of lung and its precursor, pp. 235-240
ii) Carcinoma and dysplasia of the pancreatic duct, pp. 240-248
Appendix (PDF 197 KB)
pp. 249-255.
Literature (PDF 53 KB)
pp. 257-264.
Acknowledgment (PDF 20 KB)
p. 265.
